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BKCa activator-1

CAT: 0013-GTR19249217-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249217-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BKCa activator-1 (Compound 51b) is an orally bioavailable small molecule that activates BKCa channels (EC50 = 2.82 μM), inducing membrane hyperpolarization to relax smooth muscle. Research applications include studying hypertension and airway hyperreactivity, supported by in vivo data showing efficacy in reducing blood pressure in SHR models and suppressing cough in guinea pigs.
Field of Research
Pharmacology & Drug Discovery
Smiles
FC1=C (F) C (OC2=CC=C (NCCCCCN3CCOCC3) C=C2O) =C (F) C (F) =C1C (F) (F) F
Molecular Formula
C22H23F7N2O3
Molecular Weight
496.418
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
T205564-01BKCa activator-1
B2103-06Slo1 (BKCa, BKCA alpha, BK channel, BK channel alpha subunit, Kcnma1, Potassium Large Conductance Calcium-Activated Channel, subfamily M, alpha member 1)
MBS6243033-01Slo1 (BKCa, BKCA alpha, BK channel, BK channel alpha subunit, Kcnma1, Potassium Large Conductance Calcium-Activated Channel, subfamily M, alpha member 1) (Biotin)
MBS6244099-01Slo1 (BKCa, BKCA alpha, BK channel, BK channel alpha subunit, Kcnma1, Potassium Large Conductance Calcium-Activated Channel, subfamily M, alpha member 1) (HRP)
MBS6241968-01Slo1 (BKCa, BKCA alpha, BK channel, BK channel alpha subunit, Kcnma1, Potassium Large Conductance Calcium-Activated Channel, subfamily M, alpha member 1) (AP)
B2103-06-APCSlo1 (BKCa, BKCA alpha, BK channel, BK channel alpha subunit, Kcnma1, Potassium Large Conductance Calcium-Activated Channel, subfamily M, alpha member 1) (APC)
B2103-06-ML490Slo1 (BKCa, BKCA alpha, BK channel, BK channel alpha subunit, Kcnma1, Potassium Large Conductance Calcium-Activated Channel, subfamily M, alpha member 1) (MaxLight 490)
MBS6246231-01Slo1 (BKCa, BKCA alpha, BK channel, BK channel alpha subunit, Kcnma1, Potassium Large Conductance Calcium-Activated Channel, subfamily M, alpha member 1) (MaxLight 550)
B2103-06-ML650Slo1 (BKCa, BKCA alpha, BK channel, BK channel alpha subunit, Kcnma1, Potassium Large Conductance Calcium-Activated Channel, subfamily M, alpha member 1) (MaxLight 650)
B2103-06-APSlo1 (BKCa, BKCA alpha, BK channel, BK channel alpha subunit, Kcnma1, Potassium Large Conductance Calcium-Activated Channel, subfamily M, alpha member 1) (AP) discontinued

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