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GE1111

CAT: 0013-GTR19249114-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249114-01Size:25 mg
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Description
GE1111 is a small molecule MRGPRX2 antagonist (IC50 = 9.42 μM) that inhibits mast cell degranulation (IC50 = 4.7 μM) . It shows antiallergic and anti-inflammatory activity in vivo, as demonstrated in the C48/80-induced systemic anaphylaxis model, making it a useful research tool for studying mast cell-mediated disorders.
CAS Number
2883669-12-1
Field of Research
Pharmacology & Drug Discovery
Smiles
O=CC1=CC=2C=C (C=C3C=CC (O) =C (C32) C1C) C4=CC=5C=CC (=CC5C=C4C (=O) OC) NC (=O) N
Molecular Formula
C28H22N2O5
Molecular Weight
466.485
Storage Conditions
-20°C
Notes
For research use only.

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