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DNMT1-IN-5

CAT: 0013-GTR19249067-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249067-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DNMT1-IN-5 (Compound 55) is a dual inhibitor of DNMT1 and DNMT3A with IC50 values of 2.42 μM and 14.4 μM, respectively. It demonstrates broad antiproliferative activity in cancer cell lines, induces cell cycle arrest and apoptosis, and shows in vivo efficacy in a TMD-8 xenograft model.
CAS Number
2982511-19-1
Field of Research
Cell Biology, Epigenetics & Chromatin
Smiles
FC1=NC=CC (=C1) C=2N=C (NC3CCN (C) CC3) C=4C=CN (C4N2) CCCN5CCCC5
Molecular Formula
C24H32FN7
Molecular Weight
437.556
Storage Conditions
-20°C
Notes
For research use only.

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