Human IL-12B p40 Recombinant Rabbit Monoclonal Antibody [PSH02-58] - BSA and Azide free (Detector)

Human IL-12B p40 Recombinant Rabbit Monoclonal Antibody [PSH02-58] - BSA and Azide free (Detector)

• Description: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
• Product Name Alternative: CLMF antibody CLMF p40 antibody CLMF2 antibody Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody IL 12 subunit p40 antibody IL 12B antibody IL-12 subunit p40 antibody IL-12B antibody IL12 p40 antibody IL12 subunit p40 antibody IL12B antibody IL12B_HUMAN antibody interleukin 12 beta chain antibody Interleukin 12 p40 antibody Interleukin 12 subunit beta antibody Interleukin 12B antibody Interleukin-12 subunit beta antibody natural killer cell stimulatory factor 40 kD subunit antibody NK cell stimulatory factor chain 2 antibody NKSF antibody NKSF2 antibody
• Abbreviation: Interleukin-12 subunit beta IL-12B Cytotoxic lymphocyte maturation factor 40 kDa subunit (CLMF p40) IL-12 subunit p40 NK cell stimulatory factor chain 2 (NKSF2) IL12B NKSF2
• CAS Number: 9000-83-3
• Swiss Prot: P29460 Human
• Cellular Locus: Secreted
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Recombinant protein within Human IL12B/P40 aa 23-328 (P29460).
• Isotype: IgG
• Clone: PSH02-58
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: ELISA (Det)
• Positive Control: Recombinant IL-12B p40 protein.
• Concentration: 1 mg/mL
• Dilution: ELISA (Det): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH02-57] to Human IL-12B p40 (Capture) (HA721834) and recombinant standard human 12B p40 (HA210655) as the standard. The reference range value is 30.9-2500pg/ml.
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4).
• Molecular Weight: Predicted band size: 37 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes