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Hidrosmin

CAT: 0804-HY-105946Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-105946Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Hidrosmin, a flavonoid, is derived from Diosmin. hidrosmin exerts a beneficial effect against diabetic nephropathy (DN) by reducing inflammation, oxidative stress, and senescence pathways. Hidrosmin can be used for the research of venous insufficiency and diabetes mellitus[1].
CAS Number
115960-14-0
UNSPSC
12352005
Target
Interleukin Related; NADPH Oxidase
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/hidrosmin.html
Smiles
OCCOC1=C2C(OC(C3=CC(O)=C(C=C3)OC)=CC2=O)=CC(O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)O)O)O)=C1
Molecular Formula
C30H36O16
Molecular Weight
652.60
References & Citations
[1]Jiménez-Castilla L, et al. Nephroprotective Effects of Synthetic Flavonoid Hidrosmin in Experimental Diabetic Nephropathy. Antioxidants (Basel) . 2021 Nov 29;10 (12) :1920.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
IL-1; NOX1; NOX4

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