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AF64394

CAT: 0804-HY-12664-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12664-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AF64394 is a GPR3 inverse agonist, with a pIC50 of 7.3.
CAS Number
1637300-25-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Orphan GPCR; Orphan Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/AF64394.html
Purity
98.02
Solubility
DMSO : ≥ 125 mg/mL
Smiles
ClC1=CC(OC(C)C)=C(CNC2=CC(C3=CC=CC=C3)=NC4=NC=NN42)C=C1
Molecular Formula
C21H20ClN5O
Molecular Weight
393.87
Precautions
H302, H315, H319, H335
References & Citations
[1]Jensen T, et al. The identification of GPR3 inverse agonist AF64394; the first small molecule inhibitor of GPR3 receptor function. Bioorg Med Chem Lett. 2014 Nov 15;24 (22) :5195-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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