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AGN 196996

CAT: 0013-GTR19244404-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19244404-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ (Ki=1087 nM) and RARγ (Ki=8523 nM) .IC50 value: 2 nM (Ki) Target: RARα antagonist AGN 196996 shows no activity in transactivation assays, but instead block the gene transcriptional activity induced by ATRA and other RAR agonists.
CAS Number
958295-17-5
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (518.33 mM; Ultrasonic)
Smiles
CCOc1c (Br) cc (cc1C (=O) c1ccc (C) cc1) C (=O) Nc1ccc (cc1) C (O) =O
Molecular Formula
C24H20BrNO5
Molecular Weight
482.32
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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