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A 839977

CAT: 0013-GTR19244344-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19244344-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A 839977 is a P2X7 selective antagonist; it blocks BzATP-evoked calcium influx at recombinant human, rat and mouse P2X7 receptors (IC50 values are 20 nM, 42 nM and 150 nM respectively) and reduces inflammatory and neuropathic pain in animal models; the antihyperalgesic effects of P2X7 receptor blockadeare mediated by blocking the release of IL-1beta.
CAS Number
870061-27-1
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (241.98 mM; Ultrasonic)
Smiles
Clc1cccc (c1Cl) -n1nnnc1NCc1ccccc1Oc1ccccn1
Molecular Formula
C19H14Cl2N6O
Molecular Weight
413.26
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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