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PD180970

CAT: 0013-GTR19244166-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19244166-01Size:100 mg
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Description
PD180970 is a highly potent and ATP-competitive p210Bcr-Abl kinase inhibitor, with an IC50 of 5 nM for inhibiting the autophosphorylation of p210Bcr-Abl. PD180970 also inhibits Src and KIT kinase with IC50s of 0.8 nM and 50 nM, respectively. PD180970 indcues apoptosis of K562 leukemic cells, and can be used for chronic myelogenous leukemia research.
CAS Number
287204-45-9
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 100 mg/mL (232.95 mM; Ultrasonic)
Smiles
Cc1cc (Nc2ncc3cc (-c4c (Cl) cccc4Cl) c (=O) n (C) c3n2) ccc1F
Molecular Formula
C21H15Cl2FN4O
Molecular Weight
429.27
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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CatalogName
HY-103274-01PD180970

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