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CMLD-2

CAT: 0013-GTR19244089-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19244089-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CMLD-2, an inhibitor of HuR-ARE interaction, competitively binds HuR protein disrupting its interaction with adenine-uridine rich elements (ARE) -containing mRNAs (Ki=350 nM) . CMLD-2 induces apoptosis exhibits antitumor activity in different cancer cells as colon, pancreatic, thyroid and lung cancer cell lines. Hu antigen R (HuR) is an RNA binding protein, can regulate target mRNAs stability and translation.
CAS Number
958843-91-9
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (97.36 mM; Ultrasonic)
Smiles
COc1ccc (cc1) C (CC (=O) N1CCCC1) c1c (OC) cc (OC) c2c (cc (=O) oc12) -c1ccccc1
Molecular Formula
C31H31NO6
Molecular Weight
513.58
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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