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MSC-4381

CAT: 0013-GTR19244047-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19244047-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MSC-4381 (MCT4-IN-1) is an orally active and selective monocarboxylate transporter 4 (MCT4/SLC16A3) inhibitor with an IC50 of 77 nM and a Ki of 11 nM. MSC-4381 targets to the cytosolic domain of MCT4. MSC-4381 results in lactate efflux inhibition and reduction of cellular viability in MCT4 high expressing cells. MSC-4381 has the potential for MCT4 transporter inhibition research. MSC-4381 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
2445185-57-7
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 83.33 mg/mL (154.90 mM; Ultrasonic (<60°C)
Smiles
CCOc1ccc (c2ncccc12) S (=O) (=O) Nc1ccc (Cl) cc1C#Cc1cnc (cc1OC) C (O) =O
Molecular Formula
C26H20ClN3O6S
Molecular Weight
537.97
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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