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Thiolutin

CAT: 0013-GTR19243767-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19243767-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thiolutin (Acetopyrrothin) is a disulfide-containing antibiotic and anti-angiogenic compound produced by Streptomyces. Thiolutin inhibits the JAMM metalloproteases Csn5, Associated-molecule-with-the-SH3-Domain-of-STAM (AMSH) and Brcc36. Thiolutin is a potent and selective inhibitor of endothelial cell adhesion accompanied by rapid induction of Heat-shock protein beta-1 (Hsp27) phosphorylation.
CAS Number
87-11-6
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 6.25 mg/mL (27.38 mM; Ultrasonic (<60°C)
Smiles
CC (=O) Nc1c2sscc2n (C) c1=O
Molecular Formula
C8H8N2O2S2
Molecular Weight
228.29
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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A4547-5Thiolutin
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