Arazine

CAT: 0804-HY-133021-01Size: 1 mg (27.2 mM x 100 μL in Methyl Acetate)Dry Ice: NoHazardous: No
CAT#:0804-HY-133021-01Size:1 mg (27.2 mM x 100 μL in Methyl Acetate)
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Description
Arazine (N-Acetyl-S-farnesyl-L-cysteine) is a cell-permeable modulator of G protein and G-protein coupled receptor signaling. Arazine can be a a substrate for isoprenylcysteine methyltransferase by competing with prenylated G protein or its receptors site[1].
CAS Number
[135304-07-3]
Product Name Alternative
N-Acetyl-S-farnesyl-L-cysteine
UNSPSC
12352211
Hazard Statement
H225-H319-H336
Target
DNA Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/arazine.html
Concentration
27.2 mM * 500 μL in Methyl acetate
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C(O)[C@H](CSC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)NC(C)=O
Molecular Formula
C20H33NO3S
Molecular Weight
367.55
Precautions
P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501
References & Citations
[1]Gordon JS, et al. Topical N-acetyl-S-farnesyl-L-cysteine inhibits mouse skin inflammation, and unlike dexamethasone, its effects are restricted to the application site.J Invest Dermatol. 2008 Mar;128 (3) :643-54. Epub 2007 Sep 20.|[2]Adhami K, et al. N-acetyl-S-farnesyl-l-cysteine suppresses chemokine production by human dermal microvascular endothelial cells.Exp Dermatol. 2012 Sep;21 (9) :700-5.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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