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LYG-409

CAT: 0013-GTR19249429-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249429-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LYG-409 is a potent, orally bioavailable GSPT1 degrader demonstrating significant anti-tumor efficacy in vivo, with over 94% TGI in AML and prostate cancer models. It degrades GSPT1 in vitro with a DC50 of 7.87 nM and inhibits KG-1 cell proliferation with an IC50 of 9.50 nM, supporting research in targeted protein degradation for oncology.
CAS Number
3053857-55-6
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C (NCC1=CC=C2C (=O) N (CC2=C1) C3C (=O) NC (=O) CC3) C4=CC=5C=C (OC (F) (F) F) C=CC5OC4
Molecular Formula
C25H20F3N3O6
Molecular Weight
515.438
Storage Conditions
-20°C
Notes
For research use only.

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A24461-100LYG-409 100mg
A24461-50LYG-409 50mg
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