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BBO-10203

CAT: 0013-GTR19241218-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241218-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BBO-10203 (Compound 758) is an orally bioavailable, selective PI3Kα-Ras interaction disruptor that binds the PI3Kα Ras-binding domain. It blocks complex formation, inhibits downstream Akt signaling without affecting basal PI3Kα activity, and shows selective antitumor efficacy in KRAS-mutant cancer models in vitro and in vivo.
CAS Number
2971769-60-3
Product Name Alternative
BBO10203
Field of Research
Signal Transduction
Purity
98.62% (May vary between batches)
Solubility
DMSO:80 mg/mL (124.86 mM)
Smiles
O=C (C=C) N1CCN2N=C (C=C2C1C) C=3N=C (C=4C=CC5=C (C=NN5C) C4) C=6C=CSC6C3C7=C (F) C=C (F) C=C7OCCOC
Molecular Formula
C34H30F2N6O3S
Molecular Weight
640.7
Storage Conditions
-20°C
Notes
For research use only.

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