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Cmp2

CAT: 0013-GTR19240112Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19240112Size:25 mg
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Description
Cmp2 is a selective TRPC6 activator suitable for treatment of synaptic deficiency in Alzheimer’s disease hippocampal neurons, Cmp2 selectively activates TRPC6 but not structurally related TRPC3 and TRPC7. Cmp2 exhibits synaptoprotective properties in culture and slices and penetrates the BBB. In vivo study indicated cmp2 (10 mg/kg I.P.) reversed deficits in synaptic plasticity in the 5xFAD mice.
CAS Number
923024-63-9
Purity
>98%
Smiles
FC1C=C (F) C=CC=1NC (=O) CCN1CCN (C2C=CC=CC=2) CC1
Molecular Formula
C19H21N3OF2
Molecular Weight
345.38634
Notes
For research use only.