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A-889425

CAT: 0013-GTR19239910-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239910-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A-889425 is a potent and selective oral TRPV1 antagonist, demonstrating species-dependent IC50 values of 34 nM (human) and 335 nM (rat) . It exhibits central nervous system penetration and has been shown in vivo to alleviate mechanical allodynia and spinal neuron hyperexcitability in rat models of inflammatory pain.
CAS Number
1072921-02-8
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C (NC1=CC=C (C=C1) S (=O) (=O) C (F) (F) F) C2=CCN (C3=NC=CC=C3C) CC2
Molecular Formula
C19H18F3N3O3S
Molecular Weight
425.42
Storage Conditions
-20°C
Notes
For research use only.

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