Products for Research Use Only

NLRP3-IN-58

CAT: 0013-GTR19239828-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239828-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NLRP3-IN-58 (DS15) is a small molecule inhibitor of the NLRP3 inflammasome, exhibiting an IC50 of 3.85 μM. At 10 μM, it suppresses IL-1β release by 33%. This compound is a useful research tool for studying NLRP3-driven inflammation in cellular models and related disease mechanisms.
CAS Number
2956014-05-2
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
O=C (NC1=CC=CC (=C1) S (=O) (=O) NC=2C=CC=CC2) CC3=CNC=4C=C (Cl) C=CC43
Molecular Formula
C22H18ClN3O3S
Molecular Weight
439.92
Storage Conditions
-20°C
Notes
For research use only.