JQ dS-4

CAT: 0013-GTR19239519Size: 2 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19239519Size:2 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

JQ dS-4 is a PROTAC degrader of BRG1/BRM/SMARCA4, achieving complete degradation in glioma models with DC50 values from 9-390 nM. It reduces viability in H3K27M glioma, prostate, thyroid, and salivary gland cancer cell lines, supporting its investigation in oncology research for both in vitro and in vivo applications.

CAS Number

2688882-69-9

Field of Research

Epigenetics & Chromatin

Smiles

O=C (NC=1C=CN=C (Cl) C1) NC=2C=CN=C (C#CC3=CC=CC (=C3) C (=O) NCCCCNC4=CC=CC=5C (=O) N (C (=O) C45) C6C (=O) NC (=O) CC6) C2

Molecular Formula

C37H31ClN8O6

Molecular Weight

719.15

Storage Conditions

-20°C

Notes

For research use only.

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