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MS182

CAT: 0013-GTR19239210-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239210-01Size:50 mg
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Description
MS182 (compound 11) is an Acetylation Targeting Chimera (AceTAC) that recruits p300/CBP to mutant p53 Y220C, inducing its site-specific acetylation at K382 with an ACE50 of 1.52 μM. It exhibits anti-proliferative activity in cancer cell lines and demonstrates bioavailability in mice, supporting its use in targeted protein acetylation and oncology research.
CAS Number
3034773-62-8
Field of Research
Cell Biology
Smiles
O=C (NCCOC1=CC=C (C=C1F) CCC2=NC=3C=C (C=CC3N2CCN4CCOCC4) C=5C (=NOC5C) C) CCOCCOCCOCCNCC=6C=CC7=C (C6) C=8C=CC (=CC8N7CC) C=9SC=C (C9) C
Molecular Formula
C57H68FN7O7S
Molecular Weight
1014.26
Storage Conditions
-20°C
Notes
For research use only.

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