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JMV7048

CAT: 0013-GTR19238441-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238441-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JMV7048 is a potent PROTAC degrader of PXR (DC50 = 379 nM) that recruits the CRBN E3 ligase to induce PXR ubiquitination and proteasomal degradation. This activity enhances chemosensitivity in colorectal cancer stem cells and delays tumor recurrence in vivo, making it a valuable research tool for studying PXR in oncology and drug resistance.
Field of Research
Pharmacology & Drug Discovery
Storage Conditions
-20°C
Notes
For research use only.

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