Products for Research Use Only

EGFR-IN-120

CAT: 0013-GTR19238371-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238371-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-120 (Compound 11eg) is an orally bioavailable EGFR inhibitor with potent, selective activity against the EGFR L858R/T790M/C797S triple mutant (IC50 = 0.053 μM) . It suppresses mutant EGFR signaling and downstream pathways, leading to cell cycle arrest, apoptosis, and inhibition of NSCLC cell proliferation in vitro.
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.