Products for Research Use Only

PF-DcpSi

CAT: 0013-GTR19237997-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19237997-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-DcpSi is a potent small molecule inhibitor of the mRNA decapping scavenger enzyme DcpS, exhibiting an IC50 of 0.11 nM. In vivo, intraperitoneal administration at 30 mg/kg ameliorates the disease phenotype in a spinal muscular atrophy (SMA) mouse model, supporting its use in neurodegenerative disease research.
CAS Number
2092917-19-4
Smiles
N#CC1=CC (F) =CC (OCC=2C=CC=C3N=C (N=C (N) C32) N) =C1
Molecular Formula
C16H12FN5O
Molecular Weight
309.3
Storage Conditions
-20°C
Notes
For research use only.