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Sauristolactam

CAT: 0804-HY-118482-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-118482-01Size:10 mg
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Description
Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus chinensis, has significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells[1]. Sauristolactam also inhibits the receptor activator of nuclear factor-κB ligand (RANKL) -induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation[2].
CAS Number
128533-02-8
Product Name Alternative
Saurolactam
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Sauristolactam.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=C3C1=CC(O)=C(C3=C4C(C=CC=C4)=C2)OC)C
Molecular Formula
C17H13NO3
Molecular Weight
279.29
References & Citations
[1]Kim SR, et al. Aristolactam BII of Saururus chinensis attenuates glutamate-induced neurotoxicity in rat cortical cultures probably by inhibiting nitric oxide production. Planta Med. 2004 May;70 (5) :391-6.|[2]Li Z, et al. Saurolactam Inhibits Proliferation, Migration, and Invasion of Human Osteosarcoma Cells. Cell Biochem Biophys. 2015 Jul;72 (3) :719-26.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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