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Eptifibatide

CAT: 0013-GTR19236811-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19236811-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Eptifibatide is a potent glycoprotein IIb/IIIa antagonist (GPIIb/IIIa; Kd = 120 nM) that inhibits platelet aggregation. Eptifibatide prevents binding of the adhesion proteins fibrinogen and von Willebrand factor to GPIIb/IIIa on the surface of activated platelets to prevent aggregation and thrombus formation. It inhibits ADP-induced citrated blood aggregation (IC50 = 0.11-0.22 μg/ml) in vitro and in vivo (IC50 = 52 μg/ml in porcine plasma) . Formulations containing eptifibatide have been used to reduce risk of thrombolysis in myocardial infarction in patients undergoing percutaneous coronary intervention.
CAS Number
188627-80-7
Field of Research
Pharmacology & Drug Discovery
Purity
>98%
Smiles
S1C ([H]) ([H]) [C@@] ([H]) (C (N ([H]) [H]) =O) N ([H]) C ([C@]2 ([H]) C ([H]) ([H]) C ([H]) ([H]) C ([H]) ([H]) N2C ([C@] ([H]) (C ([H]) ([H]) C2=C ([H]) N ([H]) C3=C ([H]) C ([H]) =C ([H]) C ([H]) =C23) N ([H]) C ([C@] ([H]) (C ([H]) ([H]) C (=O) O[H]) N ([H]) C (C ([H]) ([H]) N ([H]) C ([C@] ([H]) (C ([H]) ([H]) C ([H]) ([H]) C ([H]) ([H]) C ([H]) ([H]) /N=C (\N ([H]) [H]) /N ([H]) [H]) N ([H]) C (C ([H]) ([H]) C ([H]) ([H]) S1) =O) =O) =O) =O) =O) =O
Molecular Formula
C35H49N11O9S2
Molecular Weight
831.9619
Notes
For research use only.

Alternative Products

CatalogName
PT_40510-01Eptifibatide Human (Eptifibatide Human)
H-6654.0005Eptifibatide

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