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Glucocorticoid receptor modulator 3

CAT: 0013-GTR19236459-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19236459-01Size:25 mg
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Description
Glucocorticoid receptor modulator3 (Payload 6) is a potent thioester-based GR modulator with an IC50 of 0.6 nM. Its rapid hepatic metabolism minimizes systemic exposure, making it a suitable candidate for targeted ADC therapies in autoimmune disease research, as supported by studies in both cellular and preclinical models.
CAS Number
2688785-13-7
Field of Research
Metabolism Research
Smiles
O (C (=O) C1=CC (N) =C (F) C=C1) [C@@]2 (C (SCF) =O) [C@]3 (C) [C@@] (C[C@H]2C) ([C@]4 ([C@] (F) ([C@@H] (O) C3) [C@]5 (C) C (CC4) =CC (=O) C=C5) [H]) [H]
Molecular Formula
C29H32F3NO5S
Molecular Weight
563.63
Storage Conditions
-20°C
Notes
For research use only.

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