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C5aR1 antagonist 2

CAT: 0013-GTR19236168-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19236168-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
C5aR1 antagonist 2 (Compound 6a) is a potent, orally bioavailable small molecule inhibitor of the C5a receptor, demonstrating IC50 values of 21 nM (DISCO) and 3 nM (migration) . It is a valuable research tool for studying C5a-mediated neutrophil recruitment in models of acute and chronic inflammatory diseases.
CAS Number
2365161-92-6
Field of Research
Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery
Smiles
C (N1C=2C (N (C1=O) C3CCN (CC3) C4=C (C) C=CC=C4C) =CC=CC2OC) C5=C (C (F) (F) F) C=CC=C5
Storage Conditions
-20°C
Notes
For research use only.

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