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FLS-359

CAT: 0013-GTR19235361-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19235361-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FLS-359 is a selective, orally bioavailable allosteric SIRT2 modulator (IC50 = 3 μM) . It exhibits broad-spectrum antiviral activity against RNA and DNA viruses by inhibiting viral genome replication, making it a useful research tool for studying virology and sirtuin biology in cellular and animal models.
CAS Number
2309398-79-4
Field of Research
Epigenetics & Chromatin, Molecular Biology
Smiles
CC=1N (C=2C=C3C (=CC2) CCN (C3) C=4SC (CC5=CC=C (C=C5) N6C=CC=N6) =CN4) C=C (C) N1
Molecular Formula
C27H26N6S
Molecular Weight
466.6
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

7-(2,4-dimethyl-1H-imidazol-1-yl)-2-(5-{[4-(1H-pyrazol-1-yl)phenyl]methyl}-1,3-thiazol-2-yl)-1,2,3,4-tetrahydroisoquinoline
CAS Number2309398-79-4
PubChem CID138571253
IUPAC Name2-[7-(2,4-dimethylimidazol-1-yl)-3,4-dihydro-1H-isoquinolin-2-yl]-5-[(4-pyrazol-1-ylphenyl)methyl]-1,3-thiazole
Molecular FormulaC27H26N6S
Molecular Weight466.6
XLogP5.4
Topological Polar Surface Area80
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Heavy Atom Count34
Formal Charge0
Complexity672
SMILES
CC1=CN(C(=N1)C)C2=CC3=C(CCN(C3)C4=NC=C(S4)CC5=CC=C(C=C5)N6C=CC=N6)C=C2
InChI
InChI=1S/C27H26N6S/c1-19-17-32(20(2)30-19)25-9-6-22-10-13-31(18-23(22)15-25)27-28-16-26(34-27)14-21-4-7-24(8-5-21)33-12-3-11-29-33/h3-9,11-12,15-17H,10,13-14,18H2,1-2H3
InChIKey
JRPPFSVORXBCPF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 7-(2,4-dimethyl-1H-imidazol-1-yl)-2-(5-{[4-(1H-pyrazol-1-yl)phenyl]methyl}-1,3-thiazol-2-yl)-1,2,3,4-tetrahydroisoquinoline
CAS: 2309398-79-4
CID: 138571253
Formula: C27H26N6S
MW: 466.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight466.6
XLogP35.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass466.19396603
Monoisotopic Mass466.19396603
Topological Polar Surface Area80 Ų
Heavy Atom Count34
Formal Charge0
Complexity672
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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