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Gambogic amide

CAT: 0013-GTR19235340-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19235340-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gambogic amide is a selective TrkA agonist that binds its cytoplasmic juxtamembrane domain, inducing receptor dimerization and activating Akt and MAPK pathways. It exhibits neuroprotective effects in vitro against glutamate toxicity and shows enhanced efficacy in vivo in a transient MCAO stroke model, supporting research in neurodegeneration and ischemia.
CAS Number
286935-60-2
Field of Research
Signal Transduction
Smiles
C (/C=C (\C (N) =O) /C) [C@@]12[C@]34C (C (=O) C=5C (O3) =C (CC=C (C) C) C6=C (C5O) C=C[C@] (CCC=C (C) C) (C) O6) =CC (C1=O) (C[C@]4 (C (C) (C) O2) [H]) [H]
Molecular Formula
C38H45NO7
Molecular Weight
627.77
Storage Conditions
-20°C
Notes
For research use only.

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