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GSK_WRN3

CAT: 0013-GTR19235305-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19235305-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK_WRN3 is a selective, covalent inhibitor of the WRN protease (IC50 = 8.6 μM) that targets Cys727. It suppresses the growth of MSI tumor models in vitro by inducing DNA double-strand breaks and blocking proliferation, making it a valuable tool for oncology research on DNA damage response pathways.
CAS Number
2923009-50-9
Field of Research
Cell Biology, Molecular Biology
Smiles
OC1=C (NC (=O) C (C (N[C@@H]2C=CS (=O) (=O) C2) =O) =C1) C3CCCCC3
Molecular Formula
C16H20N2O5S
Molecular Weight
352.40
Storage Conditions
-20°C
Notes
For research use only.

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