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JCS-1

CAT: 0013-GTR19241325-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241325-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JCS-1 is a potent, nanomolar DcpS PROTAC degrader (DC50 = 87 nM in MOLM-14 cells) that utilizes an RG3039-based warhead to recruit the VHL E3 ligase. This tool compound enables the study of DcpS-dependent mechanisms in acute myeloid leukemia research and related genetic disorders in cellular models.
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Molecular Formula
C62H79N9O12S
Molecular Weight
1174.41
Storage Conditions
-20°C
Notes
For research use only.

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