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TMU 35435

CAT: 0013-GTR19239196-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239196-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TMU 35435 is a histone deacetylase (HDAC) inhibitor that radiosensitizes triple-negative breast cancer (TNBC) cells. It functions by promoting proteotoxic stress, autophagy, and inhibiting DNA-PKcs via ubiquitination to impair non-homologous end joining (NHEJ) DNA repair, as demonstrated in vitro.
CAS Number
2231800-32-9
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Smiles
O=C (NCCCCCCC (=O) NO) C1=CC=CC=2C=C3C=CC=C (C3=NC21) C
Molecular Formula
C22H25N3O3
Molecular Weight
379.45
Storage Conditions
-20°C
Notes
For research use only.

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