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γ-Secretase-IN-2

CAT: 0013-GTR19234108-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234108-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
γ-secretase-IN-2 (Compound 36) is a potent and selective γ-secretase inhibitor with an IC50 of 0.07 nM. This small molecule is a valuable research tool for studying Notch signaling and amyloid precursor protein (APP) processing in both cellular and animal models of Alzheimer's disease and oncology.
CAS Number
564462-36-8
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Smiles
N (C ([C@@H] ([C@@H] (CO) C1=CC (F) =C (F) C=C1) C2=CC=C (F) C=C2) =O) [C@H]3N=C (C=4C (NC3=O) =CC=CC4) C5=CC=CC=C5
Molecular Formula
C31H24F3N3O3
Molecular Weight
543.54
Storage Conditions
-20°C
Notes
For research use only.

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