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PARP1-IN-20

CAT: 0013-GTR19233886-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19233886-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PARP1-IN-20 (19A10) is a potent PARP1 inhibitor with an IC50 of 4.62 nM, yet it displays a significantly weaker PARP-trapping activity compared to Veliparib (IC50 >100 μM in MDA-MB-436 cells) . This profile makes it a useful chemical tool for studying catalytic inhibition in cancer research, applicable in both in vitro and in vivo models of BRCA-deficient cancers.
CAS Number
2659357-95-4
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Smiles
O=C (N) C=1C=CC=C2N=C (NC21) C=3C=CC (=CC3) C (=O) N4CCN (C (=O) C=5N=C (Br) SC5) CC4
Molecular Formula
C23H19BrN6O3S
Molecular Weight
539.40
Storage Conditions
-20°C
Notes
For research use only.

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