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Cdk4 Inhibitor

CAT: 0013-GTR19232926-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19232926-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PD 0332991 is a cell-permeable, ATP-competitive inhibitor selectively targeting Cdk4/6 with high potency (IC50 = 76 nM) . It induces G1 arrest by blocking Rb phosphorylation and demonstrates robust antiproliferative activity in vitro (e.g., HCT-116 cells) and in vivo tumor models, making it a key tool for cell cycle and oncology research.
CAS Number
546102-60-7
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
O=C1C2=C3C (=C4C (=C2C (=O) N1) C=5C (N4) =CC=CC5) NC=6C3=CC=C (Br) C6
Molecular Formula
C20H10BrN3O2
Molecular Weight
404.2
Storage Conditions
-20°C
Notes
For research use only.

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