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4-Hydroxyretinoic acid

CAT: 0013-GTR19231943-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19231943-01Size:100 mg
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Description
4-Hydroxyretinoic acid (4-HRA) is a naturally occurring retinoid derivative with diverse biological effects. 4-Hydroxyretinoic acid is formed from retinol catalyzed by cytochrome P-450 isozyme (s), and is mainly metabolized by the liver in the body. 4-Hydroxyretinoic acid also serves as the substrate for human liver microsomal UDP-glucuronosyltransferase (s) and recombinant UGT2B7. 4-Hydroxyretinoic acid regulates gene expression and cell differentiation via binding to nuclear receptor RAR (Retinoic Acid Receptor), and activates RARs and RXR-alpha, to induce cancer cell apoptosis. In addition, 4-Hydroxyretinoic acid is also involved in various physiological processes such as immune regulation, neuroprotection, and anti-oxidation.
CAS Number
66592-72-1
Purity
>98%
Smiles
OC (/C=C (/C=C/C=C (/C=C/C1=C (C) C (O) CCC1 (C) C) \C) \C) =O
Molecular Formula
C20H28O3
Molecular Weight
316.43452
Notes
For research use only.

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