Products for Research Use Only
RegisterLogin

KP-457

CAT: 0013-GTR19231421-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19231421-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
KP-457 is a selective small-molecule inhibitor targeting ADAM17/TACE, effectively suppressing the enzymatic release of soluble TNFα (sTNF) . This compound is a valuable research tool for investigating TNF-mediated pathways in inflammatory and oncological disease models, both in cellular and animal studies.
CAS Number
1365803-52-6
Product Name Alternative
ADAM17, KP 457, KP457, KP-457, TNF‐α‐converting enzyme
Field of Research
Protein Biochemistry
Purity
98.33% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.32 mM) ; DMSO:100 mg/mL (208.09 mM)
Smiles
C (CS (=O) (=O) C1=CC=C (OCC#CC) C=C1) (N (C=O) O) C2=CC=C (CNS (C) (=O) =O) C=C2
Molecular Formula
C21H24N2O7S2
Molecular Weight
480.56
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19243315-01KP-81
GTR19205178-01KP-23172
GTR19150440-01KP-2067
GTR19280773-01KP-19
GTR19279928-01KP-1461
GTR19234137-01KP-302
GTR19223425-01KP-1
GTR19194107-01KP-1212
GTR19240833-01KP-14
GTR19069629KP-6

Alternative Products

CatalogName
BA8011-5KP-457
A19622-1KP-457 1mg
A19622-25KP-457 25mg
A19622-100KP-457 100mg
A19622-50KP-457 50mg
A19622-10KP-457 10mg
HY-110397G-01KP-457 (GMP)
A19622-5KP-457 5mg
A19622-10mM-DKP-457 10mM * 1mL in DMSO
HY-105419KP-19

Popular Products