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PhosTAC7

CAT: 0013-GTR19231321-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19231321-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PhosTAC7 is a heterobifunctional molecule that induces targeted dephosphorylation of FOXO3a at serine 318 by recruiting the phosphatase PP2A. This PROTAC-based degrader enables the study of FOXO3a signaling and its role in cellular processes such as apoptosis and metabolism in both in vitro and in vivo research models.
CAS Number
3016307-75-5
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.96% (May vary between batches)
Smiles
[C@H] (C (=O) N1[C@H] (C (O[C@H] (CCC2=CC (OC) =C (OC) C=C2) C3=CC (OCC (NCCOCCOCCOCCOCCOCCOCCOCCCCCCCl) =O) =CC=C3) =O) CCCC1) (CC) C4=CC (OC) =C (OC) C (OC) =C4
Molecular Formula
C58H87ClN2O17
Molecular Weight
1119.77
Storage Conditions
-20°C
Notes
For research use only.

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