2-Ethoxybenzamide

CAT: 0804-HY-B1428-01Size: 500 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B1428-01Size:500 mg
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Description
2-Ethoxybenzamide (Ethenzamide) is a nonsteroidal anti-inflammatory agent that shows analgesic and antipyretic effects. 2-Ethoxybenzamide induces melanin synthesis via cAMP response element-binding protein (CREB) phosphorylation. 2-Ethoxybenzamide can be used in the research of hypopigmentation and inflammation-related diseases[1][2].
CAS Number
[938-73-8]
Product Name Alternative
Ethenzamide
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PERK; Reactive Oxygen Species (ROS) ; Tyrosinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/2-Ethoxybenzamide.html
Purity
99.82
Solubility
DMSO : ≥ 47 mg/mL
Smiles
O=C(N)C1=CC=CC=C1OCC
Molecular Formula
C9H11NO2
Molecular Weight
165.19
Precautions
H302, H315, H319, H335
References & Citations
[1]Srinivasulu Aitipamula, et al. Pharmaceutical cocrystals of ethenzamide: structural, solubility and dissolution studies. CrystEngComm, 2012,14, 8515-8524.|[2]Kazuomi Sato, et al. 2-Ethoxybenzamide stimulates melanin synthesis in B16F1 melanoma cells via the CREB signaling pathway. Mol Cell Biochem. 2016 Dec;423 (1-2) :39-52.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
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