Products for Research Use Only

PLM-101

CAT: 0013-GTR19230856-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230856-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PLM-101 is an orally active small molecule anticancer agent targeting FLT3 and RET for acute myeloid leukemia research. It induces FLT3 degradation via autophagy and inhibits PI3K and Ras/ERK signaling. Its efficacy has been validated in vitro and in vivo, including in mouse MV4-11 xenograft models at oral doses of 3-40 mg/kg.
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Molecular Formula
C22H22FN5O2
Molecular Weight
407.44
Storage Conditions
-20°C
Notes
For research use only.

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