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Bcl-2-IN-11

CAT: 0013-GTR19230660-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230660-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bcl-2-IN-11 is a highly potent and selective Bcl-2 inhibitor (IC50 = 0.9 nM) with >1000-fold selectivity over Bcl-xL. Its Bcl-xL-sparing profile may reduce thrombocytopenia risk, making it a valuable research tool for studying Bcl-2-dependent cancers like acute lymphoblastic leukemia in cellular and animal models.
CAS Number
2760536-88-5
Field of Research
Cell Biology
Smiles
O=[N+] (C (C=C1S (NC (C (C=CC (N2C[C@H] (N (CC2) CC3=C (C4=CC=C (C=C4) Cl) CC (C) (CC3) C) C) =C5) =C5OC6=CN=C (NC=C7) C7=C6) =O) (=O) =O) =C (C (F) =C1) NC[C@H]8COCCO8) [O-]
Molecular Formula
C45H49ClFN7O8S
Molecular Weight
902.43
Storage Conditions
-20°C
Notes
For research use only.

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