Products for Research Use Only
RegisterLogin

Roblitinib

CAT: 0804-HY-101568-01Size: 2 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-101568-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Roblitinib (FGF-401) is an orally active and highly selective FGFR4 inhibitor with an IC50 of 1.9 nM[1]. Roblitinib has antitumor activity[2].
CAS Number
1708971-55-4
Product Name Alternative
FGF-401
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
FGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/FGF-401.html
Purity
99.67
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CN1CC(N(CC2=CC(CCCN3C(NC4=CC(NCCOC)=C(C#N)C=N4)=O)=C3N=C2C=O)CC1)=O
Molecular Formula
C25H30N8O4
Molecular Weight
506.56
Precautions
H302, H315, H319, H335
References & Citations
[1]Nicole Buschmann, et al. Ring-fused bicyclic pyridyl derivatives as fgfr4 inhibitors. WO2015059668A1.|[2]Robin A Fairhurst, et al. Discovery of Roblitinib (FGF401) as a Reversible-Covalent Inhibitor of the Kinase Activity of Fibroblast Growth Factor Receptor 4. J Med Chem. 2020 Nov 12;63 (21) :12542-12573.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
206533Roblitinib
T70258-01Roblitinib citrate
A19431-500Roblitinib 500mg
A19431-100Roblitinib 100mg
A19431-25Roblitinib 25mg
A19431-5Roblitinib 5mg
S8548-1gRoblitinib (FGF401)
A19431-50Roblitinib 50mg
A19431-10Roblitinib 10mg
A19431-2Roblitinib 2mg

Popular Products