Products for Research Use Only

DBt-10

CAT: 0013-GTR19230167-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230167-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DBt-10 is a potent and selective small molecule degrader of Bruton's tyrosine kinase (BTK) . It facilitates the targeted proteasomal degradation of BTK, making it a valuable chemical probe for investigating BTK-dependent signaling pathways in both cellular (in vitro) and animal (in vivo) models of B-cell malignancies and autoimmune diseases.
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
NCCNC1=NC (C2 (CCCCC2) C3=CC=C (Cl) C=C3) =NC4=C1C=CC (N5CCN (C (CCCC (NCCN6CCOC7 (CCN (C (CN8N=CC (C9=CC (C (C%10=C (C) C (NC (N%11CC (CC (C) (C) C) (O) C%11) =O) =CC (F) =C%10) =NC=N%12) =C%12N9) =C8) =O) CC7) C6) =O) =O) CC5) =C4
Molecular Formula
C68H86ClFN16O6
Molecular Weight
1277.96
Storage Conditions
-20°C
Notes
For research use only.