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OXA (17-33)

CAT: 0804-HY-P1341-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P1341-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
OXA (17-33) is a potent and selective orexin-1 receptor (OX1) agonist. OXA (17-33) shows a ∼23-fold selectivity for the OX1 (EC50=8.29 nM) over OX2 (187 nM) [1].
CAS Number
343268-91-7
Product Name Alternative
Orexin A (17-33) (human, mouse, rat, bovine)
UNSPSC
12352209
Target
Orexin Receptor (OX Receptor)
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/oxa-17-33.html
Purity
97.48
Solubility
H2O : ≥ 12.5 mg/mL
Smiles
OC(C=C1)=CC=C1C[C@H](N)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC2=CN=CN2)C(NCC(N[C@@H](C)C(NCC(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](C)C(N[C@@H](C)C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](O)C)C(N[C@H](C(N)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)CC3=CN=CN3)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C79H125N23O22
Molecular Weight
1748.98
References & Citations
[1]German NA, et al. Truncated Orexin Peptides: Structure-Activity Relationship Studies. ACS Med Chem Lett. 2013;4 (12) :1224-1227.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
OX1 Receptor; OX2 Receptor

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