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Dimethyl-SGD-1882

CAT: 0013-GTR19229775-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19229775-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dimethyl-SGD-1882 is a potent DNA alkylating agent derived from a pyrrolobenzodiazepine (PBD) dimer. It functions as a cytotoxic payload in antibody-drug conjugates (ADCs), disrupting DNA replication in target cells. Its mechanism is studied in both in vitro cytotoxicity assays and in vivo xenograft models for oncology research.
CAS Number
3026416-27-0
Smiles
C[C@@]12N (C (C3=CC (OC) =C (OCCCOC4=C (C=C5C (N=C[C@]6 (C) N (C=C (C7=CC=C (OC) C=C7) C6) C5=O) =C4) OC) C=C3N=C2) =O) C=C (C8=CC=C (N) C=C8) C1
Molecular Formula
C44H43N5O7
Molecular Weight
753.84
Storage Conditions
-20°C
Notes
For research use only.

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