Products for Research Use Only

Endosidin5 (ES5)

CAT: 0013-GTR19231908Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19231908Size:5 mg
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Description
Endosidine 5 (ES5), is one of the most potent small molecules interferes with recycling endosomes through Annexin A6, thereby promoting the release and expression of mRNA into the cytoplasm. The delivered mRNAs is greatly enhanced via inhibition of endocytic recycling in cells and in live mice. NAV2729 (NAV) and endosidin 5 (ES5), resulted in significant enhancement (1.5–2 folds) of LNP-mediated delivery of Fluc mRNAs. Incubation of NAV and ES5 together caused modest further increases in Fluc expression in comparison to the sole application of either compound.
CAS Number
491585-87-6
Purity
0.98
Molecular Formula
C20H18N4
Molecular Weight
314
Notes
For research use only.

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