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17β-Hydroxywortmannin

CAT: 0013-GTR19232832-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19232832-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
17β-Hydroxywortmannin is a potent, orally bioavailable inhibitor of PI-3-kinase with an IC50 of 0.5 nM. It inhibits osteoclast-mediated bone resorption (IC50=10 nM) and exhibits antitumor activity, making it a valuable tool for researching cancer, bone metabolism, and PI3K signaling pathways in both cellular and animal models.
CAS Number
58053-83-1
Field of Research
Signal Transduction
Smiles
C[C@@]12C3=C ([C@]4 ([C@] (C) (C[C@H]3OC (C) =O) [C@@H] (O) CC4) [H]) C (=O) C5=C1C (C (=O) O[C@@H]2COC) =CO5
Molecular Formula
C23H26O8
Molecular Weight
430.45
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
B2095-517β-Hydroxywortmannin
MBS393792-01Heptadecanoic-17,17,17-D3 Acid
138536-AFCytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17)
138536-AF-FITCCytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (FITC)
138536-AF-APCCytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (APC)
MBS6122211-01Cytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (HRP)
MBS6122207-01Cytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (AP)
138536-AF-PECytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (PE)
138536-AF-BiotinCytokeratin 17 (Cytokeratin-17, CK 17, CK17, CK-17, Keratin 17, Keratin-17, Keratin Type I Cytoskeletal 17) (Biotin)
INB76074-0117:0-17:1-17:0 Tg

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