Products for Research Use Only
RegisterLogin

Tetrazine-Ph-PEG5-NHS ester

CAT: 0013-GTR19226126-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19226126-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Tetrazine-Ph-PEG5-NHS ester is a heterobifunctional linker for constructing PROTAC degraders. Its tetrazine group enables bioorthogonal conjugation with TCO-modified molecules via inverse electron-demand Diels-Alder (IEDDA) click chemistry, facilitating the synthesis of compounds for targeted protein degradation studies in both cellular and animal models.
CAS Number
1682653-80-0
Product Name Alternative
Alkyl/ether, PEGs, Tetrazine Ph PEG5 NHS ester, Tetrazine-PEG5-NHS ester, TetrazinePhPEG5NHS ester, Tetrazine-Ph-PEG-5-NHS ester, Tetrazine-Ph-PEG5-NHS ester
Field of Research
Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Purity
98.08% (May vary between batches)
Smiles
O=C (ON1C (=O) CCC1=O) CCOCCOCCOCCOCCOCCC (=O) NCC2=CC=C (C=C2) C=3N=NC=NN3
Molecular Formula
C27H36N6O10
Molecular Weight
604.61
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Tetrazine-PEG5-NHS ester
CAS Number1682653-80-0
PubChem CID91757779
IUPAC Name(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[3-oxo-3-[[4-(1,2,4,5-tetrazin-3-yl)phenyl]methylamino]propoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Molecular FormulaC27H36N6O10
Molecular Weight604.6
XLogP-2.5
Topological Polar Surface Area190
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count14
Rotatable Bond Count23
Heavy Atom Count43
Formal Charge0
Complexity823
SMILES
C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCC(=O)NCC2=CC=C(C=C2)C3=NN=CN=N3
InChI
InChI=1S/C27H36N6O10/c34-23(28-19-21-1-3-22(4-2-21)27-31-29-20-30-32-27)7-9-38-11-13-40-15-17-42-18-16-41-14-12-39-10-8-26(37)43-33-24(35)5-6-25(33)36/h1-4,20H,5-19H2,(H,28,34)
InChIKey
DUPHIQYIPUTDJS-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Tetrazine-PEG5-NHS ester
CAS: 1682653-80-0
CID: 91757779
Formula: C27H36N6O10
MW: 604.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight604.6
XLogP3-2.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count14
Rotatable Bond Count23
Exact Mass604.24929137
Monoisotopic Mass604.24929137
Topological Polar Surface Area190 Ų
Heavy Atom Count43
Formal Charge0
Complexity823
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19226127-01Tetrazine-Ph-NHS ester
GTR19266046-01Tetrazine-PEG5-SS-NHS ester
GTR19224860-01Tetrazine-Ph-PEG5-Ph-tetrazine
GTR19265533-01Tetrazine-Ph-PEG17-NHS ester
GTR19177918-01Tetrazine-Ph-NHCO-C3-NHS ester
GTR19215941-01Bis-PEG5-NHS ester
GTR19258093-01TCO-PEG5-NHS ester
GTR19231702-01DBCO-PEG5-NHS ester
GTR19226513-01Fmoc-PEG5-NHS ester
GTR19265511-01Biotin-PEG5-NHS ester

Alternative Products

CatalogName
T17063-01Tetrazine-Ph-PEG5-NHS ester
MD217025-5Tetrazine-PEG5-NHS ester
T17062-01Tetrazine-Ph-NHS ester
TCL-01858-01Tetrazine-PEG5-SS-NHS ester
HY-126908ATetrazine-Ph-PEG17-NHS ester
BUP07157-01Tetrazine-Ph-NHCO-C3-NHS ester
RPC66855-01Tetrazine-NHS ester
TDC47641-01Acid-PEG5-NHS ester
572860Mal-PEG5-NHS ester
572259DBCO-PEG5-NHS ester

Popular Products