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AFP Polyclonal Antibody

CAT: 0763-D-AB-10366L-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0763-D-AB-10366L-01Size:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Abbreviation
AFP
UniProt
P02773
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant Rat Afp protein expressed by E.coli
Target
Afp; AFPD; Alpha fetoglobulin; Alpha fetoprotein; Alpha fetoprotein precursor; Alpha-1-fetoprotein; Alpha-fetoglobulin; Alpha-fetoprotein; alpha-fetoprotein; Hereditary persistence of; included; FETA; FETA; Hereditary persistence of alpha fetoprotein; HPAFP
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Developmental Biology
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
IHC 1:300-1:600
Buffer
PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · P02773

Alpha-fetoprotein

FETA_RAT · Rattus norvegicus

View on UniProt ↗
Primary accession
P02773
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Afp
Protein existence
2: Evidence at transcript level
Organism
Rattus norvegicus (Rat)
Taxonomy ID
10116
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q63032, Q63205
Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

CopperMetal-binding

Cellular component

CytoplasmSecreted

PTM

Disulfide bondGlycoproteinPhosphoproteinSulfation

Technical term

Reference proteome

Domain

RepeatSignal

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AN200018PAFP/alpha-fetoprotein Monoclonal Antibody
AN001540P-01Alpha-Fetoprotein/AFP Monoclonal Antibody (Capture)
AN001550P-01Alpha-Fetoprotein/AFP Monoclonal Antibody (Detector)
AN300030P-01Recombinant AFP/alpha-fetoprotein Monoclonal Antibody
PDEM100237-01Recombinant Mouse AFP Protein (His Tag)
PDEM100030-01Recombinant Mouse AFP Protein (His Tag)

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