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DBCO-Val-Cit-OH

CAT: 0013-GTR19225659-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19225659-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DBCO-Val-Cit-OH is a cleavable linker used in constructing antibody-drug conjugates (ADCs) for targeted cancer therapy. Its valine-citrulline dipeptide sequence is selectively cleaved by cathepsin B in the lysosomes of cancer cells, enabling the controlled release of cytotoxic payloads in both in vitro and in vivo research models.
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C (N1C2=C (C#CC3=C (C1) C=CC=C3) C=CC=C2) CCCCC (N[C@@H] (C (N[C@H] (C (O) =O) CCCNC (N) =O) =O) C (C) C) =O
Molecular Formula
C32H39N5O6
Molecular Weight
589.68
Storage Conditions
-20°C
Notes
For research use only.

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